Changes

From Variome.net

Rs10411210

11,096 bytes added, 17:17, 31 January 2018
no edit summary
<table border="1" cellpadding="1" cellspacing="1" style="width:1000px">
<tbody> <tr> <th>항목</th> <th>한글</th> <th>영문</th> </tr> <tr> <td style="text-align: center;">ID</td> <td colspan="2 " style="text-align: center;">rs10411210</td> </tr> <tr> <td style="text-align: center;">염색체</td> <td colspan="2 " style="text-align: center;">chr19</td> </tr> <tr> <td style="text-align: center;">염색체상 위치</td> <td colspan="2 " style="text-align: center;">33532300</td> </tr> <tr> <td style="text-align: center;">표준게놈 유전형</td> <td colspan="2 " style="text-align: center;">C</td> </tr> <tr> <td style="text-align: center;">위험 유전형</td> <td colspan="2 " style="text-align: center;">C</td> </tr> <tr> <td style="text-align: center;">변이 종류</td> <td>&nbsp;</td> <td>intron_variant</td> </tr> <tr> <td style="text-align: center;">유전자</td> <td>[[RHPN2]]</td> <td>[[RHPN2]]</td> </tr> <tr> <td style="text-align: center;">인족별 분포</td> <td><img alt="" src="/ckfinder/userfiles/images/rs10411210.PNG" style="height:324px; width:405px" /></td> <td>&nbsp;</td> </tr> <tr> <td style="text-align: center;">관련 표현형</td> <td>[[결장(직장)암]]</td> <td>[[Colorectal cancer]]</td> </tr> <tr> <td style="text-align: center;">설명</td> <td>rs10411210의 C 대립 유전자가 대장암과 관련이있는 것으로 보고있다.</td> <td>The C allele of rs10411210 is reported to be associated with Colorectal Cancer.</td> </tr> <tr> <td style="text-align: center;">관련 논문</td> <td>[<a href="https://www.ncbi.nlm.nih.gov/pubmed/21119214?dopt=Abstract" rel="nofollow">PMID 21119214</a><a href="https://www.snpedia.com/index.php/File:OA-icon.png"><img alt="OA-icon.png" src="https://media.snpedia.com/images/5/5b/OA-icon.png" style="height:15px; width:15px" /></a>] 인구 기반 연구에서의 대장암 감수성 영역&nbsp;: 형태학적 매개 변수와의 연관성 <p><br /> [<a href="https://www.ncbi.nlm.nih.gov/pubmed/22363440?dopt=Abstract" rel="nofollow">PMID 22363440</a><a href="https://www.snpedia.com/index.php/File:OA-icon.png"><img alt="OA-icon.png" src="https://media.snpedia.com/images/5/5b/OA-icon.png" style="height:15px; width:15px" /></a>] 결장 종양 및 인접한 정상 조직에서 확인된 대장암 위험 변형의 cis-Expression QTL 분석</p>  <p><br /> [<a href="https://www.ncbi.nlm.nih.gov/pubmed/22367214?dopt=Abstract" rel="nofollow">PMID 22367214</a><a href="https://www.snpedia.com/index.php/File:OA-icon.png"><img alt="OA-icon.png" src="https://media.snpedia.com/images/5/5b/OA-icon.png" style="height:15px; width:15px" /></a>] 대장암 감수성 유전자좌의 유전자-환경 상호 작용 특성</p>  <p>[<a href="https://www.ncbi.nlm.nih.gov/pubmed/19639606?dopt=Abstract" rel="nofollow">PMID 19639606</a><a href="https://www.snpedia.com/index.php/File:OA-icon.png"><img alt="OA-icon.png" src="https://media.snpedia.com/images/5/5b/OA-icon.png" style="height:15px; width:15px" /></a>]&nbsp;주요 복잡한 인간 질병 게놈 관련 결과에서 도출된 오즈비에서 &quot;winner&#39;s curse&quot;를 교정.</p>  <p>[<a href="https://www.ncbi.nlm.nih.gov/pubmed/20501757?dopt=Abstract" rel="nofollow">PMID 20501757</a><a href="https://www.snpedia.com/index.php/File:OA-icon.png"><img alt="OA-icon.png" src="https://media.snpedia.com/images/5/5b/OA-icon.png" style="height:15px; width:15px" /></a>] 가족성 대장암에서의 낮은 침투 감수성 변형.</p>  <p>[<a href="https://www.ncbi.nlm.nih.gov/pubmed/21071539?dopt=Abstract" rel="nofollow">PMID 21071539</a><a href="https://www.snpedia.com/index.php/File:OA-icon.png"><img alt="OA-icon.png" src="https://media.snpedia.com/images/5/5b/OA-icon.png" style="height:15px; width:15px" /></a>] 11개의 대장암 GWAS(전장유전체분석연구)의 일반화가능성 및 역학 특징은 여러 인구 집단에서 나타난다.</p>  <p>[<a href="https://www.ncbi.nlm.nih.gov/pubmed/21314996?dopt=Abstract" rel="nofollow">PMID 21314996</a><a href="https://www.snpedia.com/index.php/File:OA-icon.png"><img alt="OA-icon.png" src="https://media.snpedia.com/images/5/5b/OA-icon.png" style="height:15px; width:15px" /></a>] 7개의 저투과율 대장암 소질 유전자좌에서의 증폭자 요소와 체성 대립 유전자 불균형에 대한 체계적 검색.</p>  <p>[<a href="https://www.ncbi.nlm.nih.gov/pubmed/22045029?dopt=Abstract" rel="nofollow">PMID 22045029</a>] 3146명의 환자에서 16개의 감수성 유전자좌와 대장암 표현형의 관계.</p>  <p>[<a href="https://www.ncbi.nlm.nih.gov/pubmed/22235025?dopt=Abstract" rel="nofollow">PMID 22235025</a>] 초기에 발생한 대장암과 관련된 감수성 유전 변종.</p>  <p><br /> [<a href="https://www.ncbi.nlm.nih.gov/pubmed/23359760?dopt=Abstract" rel="nofollow">PMID 23359760</a><a href="https://www.snpedia.com/index.php/File:OA-icon.png"><img alt="OA-icon.png" src="https://media.snpedia.com/images/5/5b/OA-icon.png" style="height:15px; width:15px" /></a>] 남부 중국인의 대장암 단일 염기 다형성 연관성</p>  <p><br /> [<a href="https://www.ncbi.nlm.nih.gov/pubmed/22848671?dopt=Abstract" rel="nofollow">PMID 22848671</a><a href="https://www.snpedia.com/index.php/File:OA-icon.png"><img alt="OA-icon.png" src="https://media.snpedia.com/images/5/5b/OA-icon.png" style="height:15px; width:15px" /></a>] 임상 결과가 있는 6개의 위험 유전자좌의 11가지의 공통적인 저침투성 대장암 감수성 유전자 변이의 연관성.</p>  <p><br /> [<a href="https://www.ncbi.nlm.nih.gov/pubmed/22999960?dopt=Abstract" rel="nofollow">PMID 22999960</a><a href="https://www.snpedia.com/index.php/File:OA-icon.png"><img alt="OA-icon.png" src="https://media.snpedia.com/images/5/5b/OA-icon.png" style="height:15px; width:15px" /></a>] 대장암의 유전적 위험성의 대부분은 선종에 대한 감수성을 통해 매개 될 수 있다.</p>  <p><br /> [<a href="https://www.ncbi.nlm.nih.gov/pubmed/23434150?dopt=Abstract" rel="nofollow">PMID 23434150</a><a href="https://www.snpedia.com/index.php/File:OA-icon.png"><img alt="OA-icon.png" src="https://media.snpedia.com/images/5/5b/OA-icon.png" style="height:15px; width:15px" /></a>] 대장암과 관련된 일반적인 유전 변이가 DNA 불일치 복구 유전자 돌연변이 보인자의 위험성이 있는가?</p>  <p><br /> [<a href="https://www.ncbi.nlm.nih.gov/pubmed/24854447?dopt=Abstract" rel="nofollow">PMID 24854447</a>] 대장암 감수성 변이와 위암의 연관성 분석</p>  <p><br /> [<a href="https://www.ncbi.nlm.nih.gov/pubmed/25021488?dopt=Abstract" rel="nofollow">PMID 25021488</a>] 대장암 위험을 가진 Tgfb 신호 경로 유전자 다형성의 PWE-010 연관 : 메타 분석</p> </td> <td>[<a href="https://www.ncbi.nlm.nih.gov/pubmed/21119214?dopt=Abstract" rel="nofollow">PMID 21119214</a><a href="https://www.snpedia.com/index.php/File:OA-icon.png"><img alt="OA-icon.png" src="https://media.snpedia.com/images/5/5b/OA-icon.png" style="height:15px; width:15px" /></a>] Colorectal Cancer Susceptibility Loci in a Population-Based Study: Associations with Morphological Parameters <p><br /> [<a href="https://www.ncbi.nlm.nih.gov/pubmed/22363440?dopt=Abstract" rel="nofollow">PMID 22363440</a><a href="https://www.snpedia.com/index.php/File:OA-icon.png"><img alt="OA-icon.png" src="https://media.snpedia.com/images/5/5b/OA-icon.png" style="height:15px; width:15px" /></a>] cis-Expression QTL Analysis of Established Colorectal Cancer Risk Variants in Colon Tumors and Adjacent Normal Tissue</p>  <p><br /> [<a href="https://www.ncbi.nlm.nih.gov/pubmed/22367214?dopt=Abstract" rel="nofollow">PMID 22367214</a><a href="https://www.snpedia.com/index.php/File:OA-icon.png"><img alt="OA-icon.png" src="https://media.snpedia.com/images/5/5b/OA-icon.png" style="height:15px; width:15px" /></a>] Characterization of gene-environment interactions for colorectal cancer susceptibility loci</p>  <p>[<a href="https://www.ncbi.nlm.nih.gov/pubmed/19639606?dopt=Abstract" rel="nofollow">PMID 19639606</a><a href="https://www.snpedia.com/index.php/File:OA-icon.png"><img alt="OA-icon.png" src="https://media.snpedia.com/images/5/5b/OA-icon.png" style="height:15px; width:15px" /></a>] Correcting &quot;winner&#39;s curse&quot; in odds ratios from genomewide association findings for major complex human diseases.</p>  <p>[<a href="https://www.ncbi.nlm.nih.gov/pubmed/20501757?dopt=Abstract" rel="nofollow">PMID 20501757</a><a href="https://www.snpedia.com/index.php/File:OA-icon.png"><img alt="OA-icon.png" src="https://media.snpedia.com/images/5/5b/OA-icon.png" style="height:15px; width:15px" /></a>] Low-penetrance susceptibility variants in familial colorectal cancer.</p>  <p>[<a href="https://www.ncbi.nlm.nih.gov/pubmed/21071539?dopt=Abstract" rel="nofollow">PMID 21071539</a><a href="https://www.snpedia.com/index.php/File:OA-icon.png"><img alt="OA-icon.png" src="https://media.snpedia.com/images/5/5b/OA-icon.png" style="height:15px; width:15px" /></a>] Generalizability and epidemiologic characterization of eleven colorectal cancer GWAS hits in multiple populations.</p>  <p>[<a href="https://www.ncbi.nlm.nih.gov/pubmed/21314996?dopt=Abstract" rel="nofollow">PMID 21314996</a><a href="https://www.snpedia.com/index.php/File:OA-icon.png"><img alt="OA-icon.png" src="https://media.snpedia.com/images/5/5b/OA-icon.png" style="height:15px; width:15px" /></a>] Systematic search for enhancer elements and somatic allelic imbalance at seven low-penetrance colorectal cancer predisposition loci.</p>  <p>[<a href="https://www.ncbi.nlm.nih.gov/pubmed/22045029?dopt=Abstract" rel="nofollow">PMID 22045029</a>] Relationship between 16 susceptibility loci and colorectal cancer phenotype in 3146 patients.</p>  <p>[<a href="https://www.ncbi.nlm.nih.gov/pubmed/22235025?dopt=Abstract" rel="nofollow">PMID 22235025</a>] Susceptibility genetic variants associated with early-onset colorectal cancer.</p>  <p><br /> [<a href="https://www.ncbi.nlm.nih.gov/pubmed/23359760?dopt=Abstract" rel="nofollow">PMID 23359760</a><a href="https://www.snpedia.com/index.php/File:OA-icon.png"><img alt="OA-icon.png" src="https://media.snpedia.com/images/5/5b/OA-icon.png" style="height:15px; width:15px" /></a>] Single-nucleotide polymorphism associations for colorectal cancer in southern chinese population</p>  <p><br /> [<a href="https://www.ncbi.nlm.nih.gov/pubmed/22848671?dopt=Abstract" rel="nofollow">PMID 22848671</a><a href="https://www.snpedia.com/index.php/File:OA-icon.png"><img alt="OA-icon.png" src="https://media.snpedia.com/images/5/5b/OA-icon.png" style="height:15px; width:15px" /></a>] Association of eleven common, low-penetrance colorectal cancer susceptibility genetic variants at six risk loci with clinical outcome.</p>  <p><br /> [<a href="https://www.ncbi.nlm.nih.gov/pubmed/22999960?dopt=Abstract" rel="nofollow">PMID 22999960</a><a href="https://www.snpedia.com/index.php/File:OA-icon.png"><img alt="OA-icon.png" src="https://media.snpedia.com/images/5/5b/OA-icon.png" style="height:15px; width:15px" /></a>] Much of the genetic risk of colorectal cancer is likely to be mediated through susceptibility to adenomas.</p>  <p><br /> [<a href="https://www.ncbi.nlm.nih.gov/pubmed/23434150?dopt=Abstract" rel="nofollow">PMID 23434150</a><a href="https://www.snpedia.com/index.php/File:OA-icon.png"><img alt="OA-icon.png" src="https://media.snpedia.com/images/5/5b/OA-icon.png" style="height:15px; width:15px" /></a>] Are the common genetic variants associated with colorectal cancer risk for DNA mismatch repair gene mutation carriers?</p>  <p><br /> [<a href="https://www.ncbi.nlm.nih.gov/pubmed/24854447?dopt=Abstract" rel="nofollow">PMID 24854447</a>] Association analysis of colorectal cancer susceptibility variants with gastric cancer in a Chinese Han population</p>  <p><br /> [<a href="https://www.ncbi.nlm.nih.gov/pubmed/25021488?dopt=Abstract" rel="nofollow">PMID 25021488</a>] PWE-010 The Association Of Tgfb Signalling Pathway Gene Polymorphisms With Colorectal Cancer Risk: A Meta-analysis</p> </td> </tr> <tr> <td style="text-align: center;">비고</td> <td>표준게놈은 hg19 기준입니다.</td> <td>&nbsp;</td> </tr> </tbody>
</table>
Anonymous user

Navigation menu